Nursing Medication Card -Risperidone (Kor/Eng)

Risperidone (리스페리돈)

• 적응증: 조현병, 양극성 장애, 공격성 (치매 관련 행동 문제 포함)
• 작용 기전: 도파민 D2 및 세로토닌 5-HT2 수용체 차단
• 흡수와 대사: 경구 흡수 잘되며 간에서 CYP2D6에 의해 대사, 신장 배설
• 부작용: 체중 증가, 졸음, 추체외로 증상, 고프로락틴혈증
• 투여량: 1–6mg/일 (보통 1–2회 분할 투여)
• 간호 고려사항: 추체외로 부작용 모니터링, 낙상 예방, 자살 위험성 평가

Risperidone (Risperdal)

• 분류: 비정형 항정신병제
• 적응증: 조현병, 양극성 장애, 자폐 관련 행동 문제
• 부작용: 체중 증가, EPS(추체외로 증상), 졸림
• 간호 포인트: 추체외로 증상 모니터링, 자살 위험 평가, 정기적인 혈당/지질 검사

 

Risperidone

Antipsychotics, mood stabilizers/benzisoxazoles 

● Indications: schizophrenia조현병[증], short-term treatment of acute manic or mixed episodes associated w/ bipolar 1 disorder(PO only), maintenance treatment of bipolar 1 disorder(IM only), can be used w/ lithium or valproate, irritability associated w/ autistic disorder (PO only) 

● Therapeutic effects: decreased symptoms of psychoses, bipolar mania, autism 

● Absorption: 70% ac PO 

● Distribution: unknown 

● Metabolism&Excretion: by liver 

● ADE: CNS; neuroleptic malignant syndrome, seizures, GI; constipation, diarrhea Metab; weight gain ● Dose: PO; 2-3 mg/day up at 24hr intervals by 1mg(range 1-5mg/day) 

Risperidone

Antipsychotics, mood stabilizers/benzisoxazoles

• Indications: Schizophrenia 조현병[증] , bipolar disorder, irritability associated with autistic disorder.
• Therapeutic Effects: Antipsychotic effects through dopamine D2 and serotonin 5-HT2 receptor antagonism.
• Absorption: Rapidly absorbed orally; unaffected by food.
• Distribution: Widely distributed; crosses the blood-brain barrier.
• Metabolism & Excretion: Hepatic metabolism via CYP2D6; excreted in urine and feces.
• Adverse Effects: Extrapyramidal symptoms, weight gain, hyperprolactinemia, sedation.
• Dose: Initial: 1–2 mg/day; maintenance: 4–8 mg/day, adjusted based on response.
• Considerations: Monitor for movement disorders; assess metabolic parameters regularly.DrugBankMedscape