In Canada/nursing study

Nursing Medication Card - Naloxone (Narcan)(Kor/Eng)

Shannon.p 2025. 5. 28. 07:23
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Narcan (Naloxone)

  • 적응증: 아편류(마약) 과다복용 해독
  • 작용 기전: 아편 수용체 길항 → 진정, 호흡 억제 반전
  • 흡수와 대사: IV/IM/SC/비강 투여, 간 대사 후 신장 배설
  • 부작용: 금단 증상 (불안, 고혈압, 통증), 오심, 구토
  • 투여량: 0.4–2mg IV 반복 가능, 비강 4mg 1회
  • 간호 고려사항: 환자 의식/호흡 모니터링, 재투여 필요 여부 확인, 금단 반응 주의

Narcan (Naloxone)

  • 분류: 오피오이드 길항제
  • 적응증: 아편류 과다복용 응급처치
  • 부작용: 금단 증상(통증, 불안, 고혈압), 오심
  • 간호 포인트: 효과 짧음(30–90분), 재투여 필요할 수 있음. 기도 유지 우선!

 

Naloxone (Narcan) 

Antidotes (for opioids) / opioid antagonists 

Indications: reversal o fDNS depression and respiratory depression due to suspected opioid overdose Therapeutic effects: reversal of signs of opioid excess 

Absorption: well after IM or SUBCUT. Rapidly from nasal mucosa 

Distribution: rapid to tissues. Cross placenta 

Metabolism&Excretion: by liver 

Onset/Peak/Duration: IV: 1-2min onset, 45 min duration, IM/Subcut: 2-5min onset, >45min duration, Intranasal: 8-13min onset 

ADE: CV: ventricular arrhythmias 

Naloxone (Narcan)

  • Indications: Emergency treatment of known or suspected opioid overdose.
  • Therapeutic Effects: Opioid receptor antagonist; reverses effects of opioids.
  • Absorption: Effective via intravenous, intramuscular, subcutaneous, and intranasal routes.
  • Distribution: Rapid distribution; crosses the placenta.
  • Metabolism & Excretion: Hepatic metabolism; excreted in urine.
  • Adverse Effects: Withdrawal symptoms in opioid-dependent individuals, hypertension, tachycardia.
  • Dose: 0.4–2 mg IV/IM/subcutaneously every 2–3 minutes as needed; intranasal: 4 mg as a single dose.
  • Considerations: Monitor respiratory and cardiovascular status; repeated dosing may be necessary due to shorter half-life compared to some opioids.RxListDrugBank+1RxList+1Drugs.com+1WebMD+1
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